RAF Typhoon fighter aircraft have operated alongside French warplanes in a joint strike against an underground arms cache in Syrian territory employed by the IS group, as stated by the UK's MoD.
The facility, identified by intelligence, was thought to be housing weapons and explosive materials, the release indicated, and was located in mountains just north of Palmyra in central Syria.
"Our fighter planes employed Paveway IV guided bombs to hit a several entry passages providing entry to the depot... initial indications suggest the objective was successfully hit," officials stated.
There was no indication of any harm to civilians in the attack late on Saturday and each participating jet returned to base without incident, the defence officials confirmed.
The British jets were supported by a Voyager tanker plane.
IS - also known as the so-called Islamic State - enforced militant control over parts of both Syria and Iraq prior to its 2019 collapse.
"This strike underscores our UK leadership, and determination to work closely with our partners, to eradicate any resurgence of IS and their dangerous and violent ideologies in the area," the British Defence Secretary the Defence Secretary said.
British military aircraft have conducted surveillance missions over Syrian airspace to "prevent any attempted resurgence" of Islamic State subsequent to its routing at the climactic battle in Baghuz in the year 2019, the authorities noted.
"I must thank all the members of the UK armed forces involved in this mission for their professionalism and their valour," Healey added. "They were among numerous British personnel on duty over the festive period. This operation, to remove terrorist threats who threaten our safety, shows how British military are prepared to act, continuously, ensuring Britain's security domestically and powerful internationally."
During December, the US military carried out what it described as a "major assault" on IS targets in Syria, subsequent to an ambush killed two US servicemembers and a civilian linguist in the Palmyra area.
The United Nations estimates Islamic State still boasts between 5,000 and 7,000 fighters in both countries.